Rene Castillo, Founder and Managing Principal.
Rene Castillo is the Founder and Managing Principal of HealthPulse Advisors LLC. The firm was built on one idea: reimbursement gaps in complex care are structural features of payer contract design, and that was learned by negotiating against that design from the provider side.
HealthPulse comes at reimbursement from the provider side, sharpened by direct experience negotiating and structuring advanced-therapy and managed-care contracts with payers. Seeing exactly where contract terms and actual payment separate is built into the firm's method. The firm calls that work reimbursement architecture: the contract terms, payment rules and operating assumptions that decide what a treatment center is paid for a case.
Founder-owned. No outside investors, parent company, manufacturer or payer holds a stake. The firm's commitments to the organizations it works with, and the independence rules behind them, are published here .

Founder experience, key facts.
What these figures do and do not cover
Founder's prior professional experience, distinct from HealthPulse firm-level engagement history. Full attribution and dates below.
Founder's prior professional experience includes
Medical Service Corps, Healthcare Operations, June 2020 to 2023. Served as a healthcare administrator within the Air Force Medical Service, supporting military treatment facility operations as part of the Medical Service Corps.
Relationship Development Manager, MAIDA Initiative, 2024 to 2025. Led global partnership development for the Medical AI Data for All initiative at the Rajpurkar Lab, managing hospital and health-system relationships on IRB, governance and regulatory readiness.
Associate Research Fellow, 2023 to 2024. Health-economics research on the forces shaping healthcare costs, digital-health outcomes and provider-payment equity.
Managed Care, $2.5B portfolio, 2023 to 2025. Provider-side managed-care experience across CAR-T, TIL, HSC transplant and solid-organ programs. Negotiated single-case agreements and outlier-payment structures directly with payers.
Veteran-Owned Small Business. SAM.gov registration active through 2027. UEI: SUT9RT37ZJ83. CAGE: 1ADM1. Member: AHA, HFMA, NRHA.
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